Aqueous humor drainage describes the process by which this transparent fluid circulates and leaves the eye. This fluid is essential for maintaining the physiological balance of the ocular system. In addition, it nourishes internal eye structures and helps regulate intraocular pressure.
First, aqueous humor is produced by the ciliary bodies, which are located behind the iris. These tissues continuously secrete the fluid. Afterward, the aqueous humor enters the posterior chamber, located between the iris and the lens.
Next, the fluid flows through the pupil into the anterior chamber, which lies between the cornea and the iris. In this way, aqueous humor circulates through the front part of the eyeball.
During this circulation, aqueous humor performs several important functions. For example, it provides nutrients and oxygen to avascular structures such as the cornea and the lens. Furthermore, it removes metabolic waste produced by these tissues.
In addition to its nutritional role, aqueous humor also maintains intraocular pressure. This pressure is necessary to preserve the shape of the eye and ensure proper positioning of its internal structures. Therefore, a balance between aqueous humor production and drainage is essential.
After circulating through the anterior chamber, the fluid must be drained to prevent pressure buildup. Primarily, drainage occurs through the trabecular meshwork, a filtration structure located at the angle between the cornea and the iris.
Once filtered, the fluid enters the canal of Schlemm, a circular channel surrounding the base of the cornea. Then, aqueous humor passes through collector channels that transport it into the venous system.
Finally, the fluid is absorbed into the bloodstream. As a result, the eye maintains a balanced system of pressure and nourishment.
However, if this drainage process becomes obstructed or inefficient, intraocular pressure may increase. Consequently, this condition can lead to glaucoma, a disease that may damage the optic nerve and cause vision loss.
Therefore, understanding aqueous humor drainage is essential for studying ocular physiology and preventing pressure-related eye diseases.


